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Ongoing research projects in HOME priority topic areas

Signs

Minimal important change (MIC) for POEM; does the method of calculation affect the value and does the MIC vary by age, sex, ethonicity or baseline POEM score?
Structural validity of the POEM; would the addition of items relating to pain/soreness, hot/inflamed skin and involvement of visible sites improve the performance of the scale? Should intensity of eczema symptoms be evaluated in addition to frequency of symptoms?
What is the cross cultural validity of POEM?

Online survey of the HOME membership to gather views about what long-term control means and the advantages and disadvantages of different ways to measure long-term control.
Online focus groups to understand what long-term control of eczema means to patients and carers from around the world.
Validity, reliability and responsiveness to change of the Totally Controlled Week / Well Controlled Week and correlation with other measures such as POEM.
Study to investigate how the frequency of measurement of POEM may influence the interpretation of clinical trial results.

Initial studies are underway to establish recommended outcomes for routine practice / clinical record keeping. If you are interested in being involved in this work then please contact the HOME co-ordinator (home@nottingham.ac.uk). The protocol for this work is available here .

Centre of Evidence Based Dermatology
University of Nottingham
King's Meadow Campus
Lenton Lane, Nottingham
NG7 2NR, UK

Telephone: +44 115 8232435
Fax: +44 115 8468618
Email: HOME@nottingham.ac.uk