University of Nottingham

Roadmap for developing Core Outcome Sets (COS)

The HOME initiative has published a methodological framework to use when developing and implementing a Core Outcome Set (COS).

The paper covers the entire process of COS development, starting with defining the scope and setting of the COS, determining the core domains to be measured such as symptoms or quality of life, the identification/development and assessment of the measurement properties of potential outcome measurement instruments for the core domains, recommending core outcome instruments, and finally dissemination and implementation.

Listen to Professor Hywel Williams discuss the HOME roadmap with fellow dermatologist Dr. Robert Dellavalle.

The Harmonising Outcomes for Eczema (HOME) roadmap: A methodological framework to develop core sets of outcome measurements in dermatology
Schmitt J, Apfelbacher C, Spuls PI, Thomas KS, Simpson EL, Furue M, Chalmers J, Williams HC.  J Invest Dermatol 2015 Jan;135(1):24-30. doi: 10.1038/jid.2014.320. (View abstract)

The Harmonising Outcome Measures for Eczema (HOME) implementation roadmap
Yael A Leshem, Eric L Simpson, Christian Apfelbacher, Phyllis I Spuls, Kim S Thomas, Jochen Schmitt, Laura Howells, Louise A A Gerbens, Michael E Jacobson, Norito Katoh, Hywel C Williams
Br J Dermatol. 2023 Aug 7;ljad278. doi: 10.1093/bjd/ljad278. Online ahead of print (Abstract link)


HOME - Harmonising Outcome Measures for Eczema

Centre of Evidence Based Dermatology
University of Nottingham
King's Meadow Campus
Lenton Lane, Nottingham

Telephone: +44 115 8232435
Fax: +44 115 8468618