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Long-Term Control

The core outcome set for the long-term control of eczema is repeated measurement of the other 3 domains (signs, symptoms and quality of life). 

The core outcome set also includes a patient global measurement but the details of this have not yet been defined or agreed. Work is ongoing to develop this instrument. If you are currently developing an patient global tool related to this, or are interested in joining the working group, please contact us

Related publications

Strategies used for measuring long-term control in atopic dermatitis trials: A systematic review
Barbarot S, Rogers NK, Abuabara K, Aubert H, Chalmers J, Flohr C, Hanifin J, Naldi L, Margolis DJ, Paul C, Ridd MJ, Anna Schuttelaar ML, Simpson E, Tauber M, Volke A, Weidinger S, Wilkes SR, Wollenberg A, Thomas KS.
J Am Acad Dermatol 2016 Nov; 75(5):1038-1044. doi: 10.1016\jaad.2016.05.043 (Abstract Link)

Validation of treatment escalation as a definition of atopic eczema flares.
Thomas KS, Stuart B, O'Leary CJ, Schmitt J, Paul C, Williams HC, Langan S.
PLoS One 2015 Apr 21;10(4):e0124770. doi: 10.1371/journal.pone.0124770. (Abstract Link)

How are eczema "flares" defined? A systematic review and recommendation for future studies
Langan SM, Schmitt J, Williams HC, Smith S, thomas KS.
Br J Dermatol 2014 Mar;170(3):548-56. doi: 10.1111/bjd.12747 (Abstract Link)

HOME - Harmonising Outcome Measures for Eczema

Centre of Evidence Based Dermatology
University of Nottingham
King's Meadow Campus
Lenton Lane, Nottingham

Telephone: +44 115 8232435
Fax: +44 115 8468618