University of Nottingham

HOME II Meeting, Amsterdam, Netherlands - 2011

The HOME II working meeting was held in Amsterdam in June 2011 to build on the preliminary recommendations of the Delphi exercise.  The meeting was attended by 43 individuals from 10 countries, representing different stakeholders (patients, clinicians, methodologists, and the pharmaceutical industry).  Delegates were given evidence-based information, followed by structured group discussion and anonymous consensus voting on each study question.

Consensus was achieved in recommending that the following four outcome domains be included in the core set for atopic eczema trials:

  1. clinical signs
  2. symptoms
  3. long-term control of flares
  4. quality of life

It was also agreed that to be included in the core set, instruments to measure these outcome domains need to be valid, sensitive to change and feasible

To identify which instruments should be used, a working group for each of the four domains was then formed to carry out research required to identify the most appropriate instruments and perform validation studies as required.


Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting
Schmitt J, Apfelbacher C, Spuls PI, Thomas KS, Simpson EL, Furue M, Chalmers J, Williams HC.
Allergy 2012: Sep;67(9):1111-1117; doi 10.1111/j.1398-9995.2012.02874.x (Abstract Link)


HOME - Harmonising Outcome Measures for Eczema

Centre of Evidence Based Dermatology
University of Nottingham
King's Meadow Campus
Lenton Lane, Nottingham

Telephone: +44 115 8232435
Fax: +44 115 8468618